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Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors

The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been developed for RNA-seq from FFPE samples. However, thes...

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Detalles Bibliográficos
Autores principales: Shohdy, Kyrillus S., Bareja, Rohan, Sigouros, Michael, Wilkes, David C., Dorsaint, Princesca, Manohar, Jyothi, Bockelman, Daniel, Xiang, Jenny Z., Kim, Rob, Ohara, Kentaro, Eng, Kenneth, Mosquera, Juan Miguel, Elemento, Olivier, Sboner, Andrea, Alonso, Alicia, Faltas, Bishoy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360986/
https://www.ncbi.nlm.nih.gov/pubmed/34385467
http://dx.doi.org/10.1038/s41525-021-00231-7