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Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)

BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterized by an exaggerated immune response (a hypersensitivity response) to the fungus Aspergillus (most commonly Aspergillus fumigatus). ABPA causes airway inflammation that if left untreated can lead to bronchiectasis (...

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Autores principales: Abuzneid, Yousef S., Yaghi, Yasmine, Madia, Arein, Salhab, Nataly, Amro, Naser, Abukhalaf, Sadi A., Kharraz, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361028/
https://www.ncbi.nlm.nih.gov/pubmed/34408868
http://dx.doi.org/10.1016/j.amsu.2021.102696
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author Abuzneid, Yousef S.
Yaghi, Yasmine
Madia, Arein
Salhab, Nataly
Amro, Naser
Abukhalaf, Sadi A.
Kharraz, Mohammad
author_facet Abuzneid, Yousef S.
Yaghi, Yasmine
Madia, Arein
Salhab, Nataly
Amro, Naser
Abukhalaf, Sadi A.
Kharraz, Mohammad
author_sort Abuzneid, Yousef S.
collection PubMed
description BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterized by an exaggerated immune response (a hypersensitivity response) to the fungus Aspergillus (most commonly Aspergillus fumigatus). ABPA causes airway inflammation that if left untreated can lead to bronchiectasis (an abnormal dilation of the airways) due to the immune system and fungal spores damaging sensitive lung tissues and ultimately leading to scarring. CASE PRESENTATION: We present a case of a 32-year-old female patient who was misdiagnosed with persistent asthma and treated accordingly for several months until a reexamination was done and a diagnosis of ABPA was concluded. Treatment was altered which led to the successful recovery of the patient. CONCLUSION: A reevaluation of the patients’ condition was needed to arrive to the correct diagnosis and to put her on the correct treatment as an ABPA patient instead of persistent asthma, concluding that the medical history and physical examination are both of vital significance to stipulate a correct diagnosis.
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spelling pubmed-83610282021-08-17 Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA) Abuzneid, Yousef S. Yaghi, Yasmine Madia, Arein Salhab, Nataly Amro, Naser Abukhalaf, Sadi A. Kharraz, Mohammad Ann Med Surg (Lond) Case Report BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterized by an exaggerated immune response (a hypersensitivity response) to the fungus Aspergillus (most commonly Aspergillus fumigatus). ABPA causes airway inflammation that if left untreated can lead to bronchiectasis (an abnormal dilation of the airways) due to the immune system and fungal spores damaging sensitive lung tissues and ultimately leading to scarring. CASE PRESENTATION: We present a case of a 32-year-old female patient who was misdiagnosed with persistent asthma and treated accordingly for several months until a reexamination was done and a diagnosis of ABPA was concluded. Treatment was altered which led to the successful recovery of the patient. CONCLUSION: A reevaluation of the patients’ condition was needed to arrive to the correct diagnosis and to put her on the correct treatment as an ABPA patient instead of persistent asthma, concluding that the medical history and physical examination are both of vital significance to stipulate a correct diagnosis. Elsevier 2021-08-09 /pmc/articles/PMC8361028/ /pubmed/34408868 http://dx.doi.org/10.1016/j.amsu.2021.102696 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Abuzneid, Yousef S.
Yaghi, Yasmine
Madia, Arein
Salhab, Nataly
Amro, Naser
Abukhalaf, Sadi A.
Kharraz, Mohammad
Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title_full Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title_fullStr Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title_full_unstemmed Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title_short Misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (ABPA)
title_sort misdiagnosis of persistent asthma of a patient suffering from acute bronchopulmonary aspergillosis (abpa)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361028/
https://www.ncbi.nlm.nih.gov/pubmed/34408868
http://dx.doi.org/10.1016/j.amsu.2021.102696
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