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Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice

Total body upstream stimulatory factor 1 (USF1) deficiency in mice is associated with brown adipose tissue activation and a marked protection against the development of obesity and atherosclerotic lesions. Functional expression of USF1 has also been detected in monocytes and monocyte-derived macroph...

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Detalles Bibliográficos
Autores principales: Hoekstra, Menno, Ren, Baoyan, Laurila, Pirkka-Pekka, Hildebrand, Reeni B., Soronen, Jarkko, Frodermann, Vanessa, Li, Zhuang, Boon, Mariëtte R., Geerling, Janine J., Rensen, Patrick C. N., Jauhiainen, Matti, Van Eck, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361089/
https://www.ncbi.nlm.nih.gov/pubmed/34385562
http://dx.doi.org/10.1038/s41598-021-95858-y