Cargando…
Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice
Total body upstream stimulatory factor 1 (USF1) deficiency in mice is associated with brown adipose tissue activation and a marked protection against the development of obesity and atherosclerotic lesions. Functional expression of USF1 has also been detected in monocytes and monocyte-derived macroph...
Autores principales: | Hoekstra, Menno, Ren, Baoyan, Laurila, Pirkka-Pekka, Hildebrand, Reeni B., Soronen, Jarkko, Frodermann, Vanessa, Li, Zhuang, Boon, Mariëtte R., Geerling, Janine J., Rensen, Patrick C. N., Jauhiainen, Matti, Van Eck, Miranda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361089/ https://www.ncbi.nlm.nih.gov/pubmed/34385562 http://dx.doi.org/10.1038/s41598-021-95858-y |
Ejemplares similares
-
Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation
por: Tikka, Anna, et al.
Publicado: (2014) -
Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects
por: Soronen, Jarkko, et al.
Publicado: (2012) -
Leukocyte ABCA1 Remains Atheroprotective in Splenectomized LDL Receptor Knockout Mice
por: Lammers, Bart, et al.
Publicado: (2012) -
Augmented Atherogenesis in LDL Receptor Deficient Mice Lacking Both Macrophage ABCA1 and ApoE
por: Lammers, Bart, et al.
Publicado: (2011) -
2-Hydroxypropyl-beta-cyclodextrin Treatment Does Not Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice
por: Snip, Olga S.C., et al.
Publicado: (2022)