An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer

Neoadjuvant chemotherapy (NAC) prior to surgery and immune checkpoint therapy (ICT) have revolutionized bladder cancer management. However, stratification of patients that would benefit most from these modalities remains a major clinical challenge. Here, we combine single nuclei RNA sequencing with...

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Detalles Bibliográficos
Autores principales: Gouin, Kenneth H., Ing, Nathan, Plummer, Jasmine T., Rosser, Charles J., Ben Cheikh, Bassem, Oh, Catherine, Chen, Stephanie S., Chan, Keith Syson, Furuya, Hideki, Tourtellotte, Warren G., Knott, Simon R. V., Theodorescu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361097/
https://www.ncbi.nlm.nih.gov/pubmed/34385456
http://dx.doi.org/10.1038/s41467-021-25103-7

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