Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis

Multiple gene mutations cause familial frontotemporal lobar degeneration (FTLD) while no single gene mutations exists in sporadic FTLD. Various proteins aggregate in variable regions of the brain, leading to multiple pathological and clinical prototypes. The heterogeneity of FTLD could be one of the...

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Detalles Bibliográficos
Autores principales: Jin, Meihua, Jin, Xiaocen, Homma, Hidenori, Fujita, Kyota, Tanaka, Hikari, Murayama, Shigeo, Akatsu, Hiroyasu, Tagawa, Kazuhiko, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361101/
https://www.ncbi.nlm.nih.gov/pubmed/34385591
http://dx.doi.org/10.1038/s42003-021-02475-6

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