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Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report

INTRODUCTION: The common manifestations of gastrointestinal stromal tumors (GIST) are well established. However, jejunal diverticulosis is an uncommon phenomenon to be associated with this lesion, with its rarity compounded by the relative difficulty associated with its diagnosis. Limited literature...

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Autor principal: Chung, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361120/
https://www.ncbi.nlm.nih.gov/pubmed/34388891
http://dx.doi.org/10.1016/j.ijscr.2021.106291
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author Chung, Douglas
author_facet Chung, Douglas
author_sort Chung, Douglas
collection PubMed
description INTRODUCTION: The common manifestations of gastrointestinal stromal tumors (GIST) are well established. However, jejunal diverticulosis is an uncommon phenomenon to be associated with this lesion, with its rarity compounded by the relative difficulty associated with its diagnosis. Limited literature is available on this topic. This article examines one such case of jejunal diverticulitis as a result of a GIST, and the intervention of said disease. CASE PRESENTATION: A 69 year old lady presented with abdominal pain, vomiting, and low grade fevers, on a background of ulcerative colitis. She was peritonitic, raising concerns of an acute abdomen. Her imaging identified an intra-abdominal contained perforation, prompting a transfer to theatres overnight for a laparotomy, which identified a jejunal diverticulum, which resembled a contained perforation. This was resected, and sent for histopathological analysis, identifying the lesion as a GIST. DISCUSSION: Unlike other forms of jejunal diverticular disease, those arising from GISTs tend to present perforated, necessitating resection. This disease displays a tendency towards formation on the anti-mesenteric border of the small bowel. Additionally, this particular form of GIST shows macroscopic and histopathological uniformity across reported cases to date despite significant geographical disparity. CONCLUSION: A scant number of case reports worldwide have identified jejunal diverticulitis from GISTs. We suggest diverticula be excised if perforation is suspected, while incidental findings of such be left untouched. However, overall management should be undertaken at the discretion of the operating surgeon.
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spelling pubmed-83611202021-08-17 Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report Chung, Douglas Int J Surg Case Rep Case Report INTRODUCTION: The common manifestations of gastrointestinal stromal tumors (GIST) are well established. However, jejunal diverticulosis is an uncommon phenomenon to be associated with this lesion, with its rarity compounded by the relative difficulty associated with its diagnosis. Limited literature is available on this topic. This article examines one such case of jejunal diverticulitis as a result of a GIST, and the intervention of said disease. CASE PRESENTATION: A 69 year old lady presented with abdominal pain, vomiting, and low grade fevers, on a background of ulcerative colitis. She was peritonitic, raising concerns of an acute abdomen. Her imaging identified an intra-abdominal contained perforation, prompting a transfer to theatres overnight for a laparotomy, which identified a jejunal diverticulum, which resembled a contained perforation. This was resected, and sent for histopathological analysis, identifying the lesion as a GIST. DISCUSSION: Unlike other forms of jejunal diverticular disease, those arising from GISTs tend to present perforated, necessitating resection. This disease displays a tendency towards formation on the anti-mesenteric border of the small bowel. Additionally, this particular form of GIST shows macroscopic and histopathological uniformity across reported cases to date despite significant geographical disparity. CONCLUSION: A scant number of case reports worldwide have identified jejunal diverticulitis from GISTs. We suggest diverticula be excised if perforation is suspected, while incidental findings of such be left untouched. However, overall management should be undertaken at the discretion of the operating surgeon. Elsevier 2021-08-08 /pmc/articles/PMC8361120/ /pubmed/34388891 http://dx.doi.org/10.1016/j.ijscr.2021.106291 Text en Crown Copyright © 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Chung, Douglas
Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title_full Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title_fullStr Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title_full_unstemmed Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title_short Jejunal diverticulitis secondary to a gastrointestinal stromal tumor: A case report
title_sort jejunal diverticulitis secondary to a gastrointestinal stromal tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361120/
https://www.ncbi.nlm.nih.gov/pubmed/34388891
http://dx.doi.org/10.1016/j.ijscr.2021.106291
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