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Evaluation of acetylation and methylation in oral rinse of patients with head and neck cancer history exposed to valproic acid

Evaluate the biological action of valproic acid in the acetylation of histones and in the methylation of tumor suppressor genes via oral rinse in patients with a previous history of head and neck squamous cell carcinoma (HNSCC). Forty-two active or former smokers were included in this randomized, do...

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Detalles Bibliográficos
Autores principales: Gama, Ricardo Ribeiro, Arantes, Lidia Maria Rebolho Batista, Sorroche, Bruna Pereira, De Marchi, Pedro, Melendez, Matias Eliseo, Carvalho, Raiany Santos, de Lima, Marcos Alves, Vettore, André Luiz, Carvalho, André Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361187/
https://www.ncbi.nlm.nih.gov/pubmed/34385507
http://dx.doi.org/10.1038/s41598-021-95845-3