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Evaluation of acetylation and methylation in oral rinse of patients with head and neck cancer history exposed to valproic acid
Evaluate the biological action of valproic acid in the acetylation of histones and in the methylation of tumor suppressor genes via oral rinse in patients with a previous history of head and neck squamous cell carcinoma (HNSCC). Forty-two active or former smokers were included in this randomized, do...
Autores principales: | Gama, Ricardo Ribeiro, Arantes, Lidia Maria Rebolho Batista, Sorroche, Bruna Pereira, De Marchi, Pedro, Melendez, Matias Eliseo, Carvalho, Raiany Santos, de Lima, Marcos Alves, Vettore, André Luiz, Carvalho, André Lopes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361187/ https://www.ncbi.nlm.nih.gov/pubmed/34385507 http://dx.doi.org/10.1038/s41598-021-95845-3 |
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