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Protective efficacy of the anti-HIV broadly neutralizing antibody PGT121 in the context of semen exposure

BACKGROUND: HIV-1 infections occur following viral exposure at anogenital mucosal surfaces in the presence of semen. Semen contains immunosuppressive and pro-inflammatory factors. Semen from HIV-1-infected donors contains anti-HIV-1 antibodies. We assessed if passively infused anti-HIV-1 neutralizin...

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Detalles Bibliográficos
Autores principales:	Parsons, Matthew S., Kristensen, Anne B., Selva, Kevin J., Lee, Wen Shi, Amarasena, Thakshila, Esterbauer, Robyn, Wheatley, Adam K., Bavinton, Benjamin R., Kelleher, Anthony D., Grulich, Andrew E., Khoury, Georges, Juno, Jennifer A., Kent, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361295/ https://www.ncbi.nlm.nih.gov/pubmed/34385004 http://dx.doi.org/10.1016/j.ebiom.2021.103518

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