Cargando…
Phase I dose-escalation single centre clinical trial to evaluate the safety of infusion of memory T cells as adoptive therapy in COVID-19 (RELEASE)
BACKGROUND: Effective treatments are still needed to reduce the severity of symptoms, time of hospitalization, and mortality of COVID-19. SARS-CoV-2 specific memory T-lymphocytes obtained from convalescent donors recovered can be used as passive cell immunotherapy. METHODS: Between September and Nov...
Autores principales: | Pérez-Martínez, A., Mora-Rillo, M., Ferreras, C., Guerra-García, P., Pascual-Miguel, B., Mestre-Durán, C., Borobia, A.M., Carcas, A.J., Queiruga-Parada, J., García, I., Sánchez-Zapardiel, E., Gasior, M., De Paz, R., Marcos, A., Vicario, J.L., Balas, A., Moreno, M.A., Eguizabal, C., Solano, C., Arribas, J.R., Buckley, R.de Miguel, Montejano, R., Soria, B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361305/ https://www.ncbi.nlm.nih.gov/pubmed/34405140 http://dx.doi.org/10.1016/j.eclinm.2021.101086 |
Ejemplares similares
-
A phase I/II dose-escalation single center study to evaluate the safety of infusion of memory t cells as adoptive therapy in coronavirus pneumonia and /or lymphopenia (release)
por: Perez-Martinez, A., et al.
Publicado: (2021) -
A phase I/II dose-escalation multi-center study to evaluate the safety of infusion of natural killer cells or memory T cells as adoptive therapy in coronavirus pneumonia and/or lymphopenia: RELEASE study protocol
por: García-García, I., et al.
Publicado: (2021) -
A Phase I/II Dose-Escalation Multi-Center Study to Evaluate the Safety of Infusion of Natural Killer Cells or Memory T Cells As Adoptive Therapy in Coronavirus Pneumonia and/or Lymphopenia: (RELEASE NCT04578210)
por: Pérez-Martínez, Antonio, et al.
Publicado: (2021) -
Immunotherapy: EVALUATION OF MEMORY T CELLS AS ADOPTIVE THERAPY IN CORONAVIRUS PNEUMONIA AND/OR LYMPHOPENIA: A PHASE II CLINICAL TRIAL (RELEASE NCT04578210)
por: Ferreras, C., et al.
Publicado: (2023) -
A Phase II Randomized Multi-Center Study to Evaluate the Safety and Efficacy of Infusion of Memory T Cells As Adoptive Therapy in Coronavirus Pneumonia and/or Lymphopenia (RELEASE NCT04578210)
por: Perez, Antonio, et al.
Publicado: (2022)