Cargando…

Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression

Metabolomics in the Alzheimer’s Disease Neuroimaging Initiative cohort provides a powerful tool for mapping biochemical changes in Alzheimer’s disease, and a unique opportunity to learn about the association between circulating blood metabolites and brain amyloid-β deposition in Alzheimer’s disease....

Descripción completa

Detalles Bibliográficos
Autores principales:	Nho, Kwangsik, Kueider-Paisley, Alexandra, Arnold, Matthias, MahmoudianDehkordi, Siamak, Risacher, Shannon L, Louie, Gregory, Blach, Colette, Baillie, Rebecca, Han, Xianlin, Kastenmüller, Gabi, Doraiswamy, P Murali, Kaddurah-Daouk, Rima, Saykin, Andrew J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361396/ https://www.ncbi.nlm.nih.gov/pubmed/34396103 http://dx.doi.org/10.1093/braincomms/fcab139

Ejemplares similares

Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers
por: Nho, Kwangsik, et al.
Publicado: (2019)

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts
por: St. John-Williams, Lisa, et al.
Publicado: (2019)

Peripheral serum metabolomic profiles inform central cognitive impairment
por: Wang, Jingye, et al.
Publicado: (2020)

Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease
por: Baloni, Priyanka, et al.
Publicado: (2020)

Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
por: Arnold, Matthias, et al.
Publicado: (2020)

Circulating lipid profiles are associated with cross-sectional and longitudinal changes of central biomarkers for Alzheimer’s disease
por: Kim, Jun Pyo, et al.
Publicado: (2023)

Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease
por: Baloni, Priyanka, et al.
Publicado: (2022)

Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids
por: MahmoudianDehkordi, Siamak, et al.
Publicado: (2022)

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort
por: St John-Williams, Lisa, et al.
Publicado: (2017)

Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer’s disease and progressive supranuclear palsy
por: Batra, Richa, et al.
Publicado: (2023)

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology
por: Barupal, Dinesh Kumar, et al.
Publicado: (2019)

Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
por: Horgusluoglu, Emrin, et al.
Publicado: (2021)

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
por: Varma, Vijay R., et al.
Publicado: (2018)

Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression
por: MahmoudianDehkordi, Siamak, et al.
Publicado: (2021)

The Metabolome-Wide Signature of Major Depressive Disorder
por: Jansen, Rick, et al.
Publicado: (2023)

Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data
por: Jo, Taeho, et al.
Publicado: (2023)

Deep learning detection of informative features in tau PET for Alzheimer’s disease classification
por: Jo, Taeho, et al.
Publicado: (2020)

Myelin repair in Alzheimer’s disease: a review of biological pathways and potential therapeutics
por: Hirschfeld, Lauren Rose, et al.
Publicado: (2022)

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics
por: Han, Xianlin, et al.
Publicado: (2011)

Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication
por: Joyce, Jeremiah B., et al.
Publicado: (2021)

Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment
por: Bhattacharyya, Sudeepa, et al.
Publicado: (2019)

Metabolic Profiling of Patients with Schizophrenia
por: Kaddurah-Daouk, Rima
Publicado: (2006)

Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition
por: Risacher, Shannon L., et al.
Publicado: (2019)

Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism
por: Borkowski, Kamil, et al.
Publicado: (2023)

Fused multi-modal similarity network as prior in guiding brain imaging genetic association
por: He, Bing, et al.
Publicado: (2023)

Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease
por: Borkowski, Kamil, et al.
Publicado: (2021)

Genome-Wide Association Analysis across Endophenotypes in Alzheimer’s Disease: Main Effects and Disease Stage-Specific Interactions
por: Rosewood, Thea J., et al.
Publicado: (2023)

ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease
por: Ko, Yi-An, et al.
Publicado: (2022)

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer’s disease
por: Lee, Younghee, et al.
Publicado: (2018)

Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains
por: Varathan, Pradeep, et al.
Publicado: (2022)

Association of the top 20 Alzheimer's disease risk genes with [(18)F]flortaucipir PET
por: Stage, Eddie, et al.
Publicado: (2022)

Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature
por: Brydges, Christopher R., et al.
Publicado: (2021)

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study
por: Ramanan, Vijay K., et al.
Publicado: (2013)

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease
por: Park, Young Ho, et al.
Publicado: (2021)

Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients
por: Bhattacharyya, Sudeepa, et al.
Publicado: (2019)

Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease
por: Yan, Jingwen, et al.
Publicado: (2015)

Identification of exon skipping events associated with Alzheimer’s disease in the human hippocampus
por: Han, Seonggyun, et al.
Publicado: (2019)

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways
por: Horgusluoglu-Moloch, Emrin, et al.
Publicado: (2019)

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging
por: Yan, Qi, et al.
Publicado: (2018)

Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data
por: Jo, Taeho, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_brjak45gk5celofpksa937jnhn