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Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity

BACKGROUND: Previous reports identified proteins associated with ‘apoptosis’ following cross-linking PrP(C) with motif-specific anti-PrP antibodies in vivo and in vitro. The molecular mechanisms underlying this IgG-mediated neurotoxicity and the role of the activated proteins in the apoptotic pathwa...

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Detalles Bibliográficos
Autores principales: Adhikari, Utpal Kumar, Sakiz, Elif, Zhou, Xian, Habiba, Umma, Kumar, Sachin, Mikhael, Meena, Senesi, Matteo, Guang Li, Chun, Guillemin, Gilles J., Ooi, Lezanne, David, Monique Antoinette, Collins, Steven, Karl, Tim, Tayebi, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361482/
https://www.ncbi.nlm.nih.gov/pubmed/34394070
http://dx.doi.org/10.3389/fimmu.2021.639008