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Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity
BACKGROUND: Previous reports identified proteins associated with ‘apoptosis’ following cross-linking PrP(C) with motif-specific anti-PrP antibodies in vivo and in vitro. The molecular mechanisms underlying this IgG-mediated neurotoxicity and the role of the activated proteins in the apoptotic pathwa...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361482/ https://www.ncbi.nlm.nih.gov/pubmed/34394070 http://dx.doi.org/10.3389/fimmu.2021.639008 |