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Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity
BACKGROUND: Previous reports identified proteins associated with ‘apoptosis’ following cross-linking PrP(C) with motif-specific anti-PrP antibodies in vivo and in vitro. The molecular mechanisms underlying this IgG-mediated neurotoxicity and the role of the activated proteins in the apoptotic pathwa...
Autores principales: | Adhikari, Utpal Kumar, Sakiz, Elif, Zhou, Xian, Habiba, Umma, Kumar, Sachin, Mikhael, Meena, Senesi, Matteo, Guang Li, Chun, Guillemin, Gilles J., Ooi, Lezanne, David, Monique Antoinette, Collins, Steven, Karl, Tim, Tayebi, Mourad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361482/ https://www.ncbi.nlm.nih.gov/pubmed/34394070 http://dx.doi.org/10.3389/fimmu.2021.639008 |
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