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Tumor cell-imposed iron restriction drives immunosuppressive polarization of tumor-associated macrophages

BACKGROUND: Tumor-associated macrophages (TAM) are immunosuppressive cells that contribute to impaired anti-cancer immunity. Iron plays a critical role in regulating macrophage function. However, it is still elusive whether it can drive the functional polarization of macrophages in the context of ca...

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Detalles Bibliográficos
Autores principales:	Sun, Jia-Lei, Zhang, Ning-Ping, Xu, Ru-Chen, Zhang, Guang-Cong, Liu, Zhi-Yong, Abuduwaili, Weinire, Wang, Fu, Yu, Xiang-Nan, Shi, Xuan, Song, Guang-Qi, Wu, Hao, Liu, Tao-Tao, Shen, Xi-Zhong, Deng, Bin, Weng, Shu-Qiang, Dong, Ling, Zhu, Ji-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361643/ https://www.ncbi.nlm.nih.gov/pubmed/34389031 http://dx.doi.org/10.1186/s12967-021-03034-7

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