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Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP

INTRODUCTION: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is re...

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Detalles Bibliográficos
Autores principales: Selli, Anders L., Kuzmiszyn, Adrina K., Smaglyukova, Natalia, Kondratiev, Timofei V., Fuskevåg, Ole-Martin, Lyså, Roy A., Ravna, Aina W., Tveita, Torkjel, Sager, Georg, Dietrichs, Erik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361756/
https://www.ncbi.nlm.nih.gov/pubmed/34393818
http://dx.doi.org/10.3389/fphys.2021.695779