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Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP
INTRODUCTION: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is re...
Autores principales: | Selli, Anders L., Kuzmiszyn, Adrina K., Smaglyukova, Natalia, Kondratiev, Timofei V., Fuskevåg, Ole-Martin, Lyså, Roy A., Ravna, Aina W., Tveita, Torkjel, Sager, Georg, Dietrichs, Erik S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361756/ https://www.ncbi.nlm.nih.gov/pubmed/34393818 http://dx.doi.org/10.3389/fphys.2021.695779 |
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