Discovery of Novel Bacterial Chalcone Isomerases by a Sequence‐Structure‐Function‐Evolution Strategy for Enzymatic Synthesis of (S)‐Flavanones

Chalcone isomerase (CHI) is a key enzyme in the biosynthesis of flavonoids in plants. The first bacterial CHI (CHI(era)) was identified from Eubacterium ramulus, but its distribution, evolutionary source, substrate scope, and stereoselectivity are still unclear. Here, we describe the identification...

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Detalles Bibliográficos
Autores principales: Meinert, Hannes, Yi, Dong, Zirpel, Bastian, Schuiten, Eva, Geißler, Torsten, Gross, Egon, Brückner, Stephan I., Hartmann, Beate, Röttger, Carsten, Ley, Jakob P., Bornscheuer, Uwe T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361940/
https://www.ncbi.nlm.nih.gov/pubmed/34129275
http://dx.doi.org/10.1002/anie.202107182

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