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Multivalent Tryptophan‐ and Tyrosine‐Containing [60]Fullerene Hexa‐Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors

Unprecedented 3D hexa‐adducts of [60]fullerene peripherally decorated with twelve tryptophan (Trp) or tyrosine (Tyr) residues have been synthesized. Studies on the antiviral activity of these novel compounds against HIV and EV71 reveal that they are much more potent against HIV and equally active ag...

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Detalles Bibliográficos
Autores principales: Ruiz‐Santaquiteria, Marta, Illescas, Beatriz M., Abdelnabi, Rana, Boonen, Arnaud, Mills, Alberto, Martí‐Marí, Olaia, Noppen, Sam, Neyts, Johan, Schols, Dominique, Gago, Federico, San‐Félix, Ana, Camarasa, María‐José, Martín, Nazario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361981/
https://www.ncbi.nlm.nih.gov/pubmed/33851758
http://dx.doi.org/10.1002/chem.202101098

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