Cobaltoceniumselenolate Gold(I) Complexes: Synthesis, Spectroscopic, Structural and Anticancer Properties

Cobaltoceniumselenolate is an unusual, highly air‐sensitive, mesoionic compound containing a very soft anionic selenium donor atom. Here we explore its coordination chemistry with Au(I) metal centers and show that its hetero‐ and homoleptic gold complexes are highly colored, air‐stable compounds, wh...

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Detalles Bibliográficos
Autores principales: Menia, Daniel, Kopacka, Holger, Wurst, Klaus, Müller, Thomas, Lippmann, Petra, Ott, Ingo, Bildstein, Benno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362036/
https://www.ncbi.nlm.nih.gov/pubmed/34413703
http://dx.doi.org/10.1002/ejic.202100379
Descripción
Sumario:Cobaltoceniumselenolate is an unusual, highly air‐sensitive, mesoionic compound containing a very soft anionic selenium donor atom. Here we explore its coordination chemistry with Au(I) metal centers and show that its hetero‐ and homoleptic gold complexes are highly colored, air‐stable compounds, which were characterized by (1)H/(13)C/(31)P/(77)Se NMR, IR, UV‐Vis, HR‐MS and single crystal XRD. Cytotoxicity of these polar, water‐soluble complexes was studied against various standard cancer cell lines (A549MDA‐MB‐231, HT‐29) revealing good anticancer activity of all three complexes.

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