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Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses

BACKGROUND: Autologous bone grafts have been applied successfully to severely atrophied maxilla via a preimplant procedure. Differences in graft incorporation at the microscopic level can be the decisive factor in the choice between anterior iliac crest and calvarial bone. PURPOSE: To compare conver...

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Autores principales: Wortmann, Dagmar E., Klein‐Nulend, Jenneke, van Ruijven, Leo J., Schortinghuis, Jurjen, Vissink, Arjan, Raghoebar, Gerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362136/
https://www.ncbi.nlm.nih.gov/pubmed/34056848
http://dx.doi.org/10.1111/cid.13012
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author Wortmann, Dagmar E.
Klein‐Nulend, Jenneke
van Ruijven, Leo J.
Schortinghuis, Jurjen
Vissink, Arjan
Raghoebar, Gerry M.
author_facet Wortmann, Dagmar E.
Klein‐Nulend, Jenneke
van Ruijven, Leo J.
Schortinghuis, Jurjen
Vissink, Arjan
Raghoebar, Gerry M.
author_sort Wortmann, Dagmar E.
collection PubMed
description BACKGROUND: Autologous bone grafts have been applied successfully to severely atrophied maxilla via a preimplant procedure. Differences in graft incorporation at the microscopic level can be the decisive factor in the choice between anterior iliac crest and calvarial bone. PURPOSE: To compare conversion of anterior iliac crest bone and calvarial bone 4 months after grafting of the edentulous maxilla. MATERIALS AND METHODS: Twenty consecutive patients were randomly assigned to either anterior iliac crest (n = 10) or calvarial (n = 10) bone harvesting to reconstruct their atrophied maxillae. Biopsies were taken from both fresh bone grafts and reconstructed maxillae after 4 months healing, at time of implant placement. Micro‐CT, histomorphometric and histological analyses were performed. RESULTS: Micro‐CT analysis revealed that both the anterior iliac crest and calvarial bone grafts retained their volume and bone mass after being incorporated in the maxilla, but with a favor for calvarial bone grafts: calvarial bone grafts had a higher mineral density before and after incorporation. Both bone grafts types were well incorporated after 4 months of healing with preservation of bone volume and mineral density. Although the fresh bone biopsies were similar histomorphometrically, after 4 months of graft incorporation, the osteoid percentage and osteocyte count remained higher in the anterior iliac crest bone whereas the percentage of bone was higher in the calvarial bone grafts compared to the anterior iliac crest bone grafts. CONCLUSIONS: Both donor sites, that is, anterior iliac crest and calvarial bone, are well suited to provide a reliable and stable basis for implant placement 4 months after grafting with mineral density, porosity, and resorption rate in favor of calvarial bone grafts.
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spelling pubmed-83621362021-08-17 Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses Wortmann, Dagmar E. Klein‐Nulend, Jenneke van Ruijven, Leo J. Schortinghuis, Jurjen Vissink, Arjan Raghoebar, Gerry M. Clin Implant Dent Relat Res Original Articles BACKGROUND: Autologous bone grafts have been applied successfully to severely atrophied maxilla via a preimplant procedure. Differences in graft incorporation at the microscopic level can be the decisive factor in the choice between anterior iliac crest and calvarial bone. PURPOSE: To compare conversion of anterior iliac crest bone and calvarial bone 4 months after grafting of the edentulous maxilla. MATERIALS AND METHODS: Twenty consecutive patients were randomly assigned to either anterior iliac crest (n = 10) or calvarial (n = 10) bone harvesting to reconstruct their atrophied maxillae. Biopsies were taken from both fresh bone grafts and reconstructed maxillae after 4 months healing, at time of implant placement. Micro‐CT, histomorphometric and histological analyses were performed. RESULTS: Micro‐CT analysis revealed that both the anterior iliac crest and calvarial bone grafts retained their volume and bone mass after being incorporated in the maxilla, but with a favor for calvarial bone grafts: calvarial bone grafts had a higher mineral density before and after incorporation. Both bone grafts types were well incorporated after 4 months of healing with preservation of bone volume and mineral density. Although the fresh bone biopsies were similar histomorphometrically, after 4 months of graft incorporation, the osteoid percentage and osteocyte count remained higher in the anterior iliac crest bone whereas the percentage of bone was higher in the calvarial bone grafts compared to the anterior iliac crest bone grafts. CONCLUSIONS: Both donor sites, that is, anterior iliac crest and calvarial bone, are well suited to provide a reliable and stable basis for implant placement 4 months after grafting with mineral density, porosity, and resorption rate in favor of calvarial bone grafts. John Wiley & Sons, Inc. 2021-05-30 2021-06 /pmc/articles/PMC8362136/ /pubmed/34056848 http://dx.doi.org/10.1111/cid.13012 Text en © 2021 The Authors. Clinical Implant Dentistry and Related Research Published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Wortmann, Dagmar E.
Klein‐Nulend, Jenneke
van Ruijven, Leo J.
Schortinghuis, Jurjen
Vissink, Arjan
Raghoebar, Gerry M.
Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title_full Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title_fullStr Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title_full_unstemmed Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title_short Incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: A randomized clinical trial with histomorphometric and micro‐CT analyses
title_sort incorporation of anterior iliac crest or calvarial bone grafts in reconstructed atrophied maxillae: a randomized clinical trial with histomorphometric and micro‐ct analyses
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362136/
https://www.ncbi.nlm.nih.gov/pubmed/34056848
http://dx.doi.org/10.1111/cid.13012
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