Cargando…
Elucidating the structure and functions of Resolvin D6 isomers on nerve regeneration with a distinctive trigeminal transcriptome
Innervation sustains cornea integrity. Pigment epithelium‐derived factor (PEDF) plus docosahexaenoic acid (DHA) regenerated damaged nerves by stimulating the synthesis of a new stereoisomer of Resolvin D6 (RvD6si). Here, we resolved the structure of this lipid isolated from mouse tears after injured...
Autores principales: | Pham, Thang L., Kakazu, Azucena H., He, Jiucheng, Nshimiyimana, Robert, Petasis, Nicos A., Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362171/ https://www.ncbi.nlm.nih.gov/pubmed/34245621 http://dx.doi.org/10.1096/fj.202100686R |
Ejemplares similares
-
Novel RvD6 stereoisomer induces corneal nerve regeneration and wound healing post-injury by modulating trigeminal transcriptomic signature
por: Pham, Thang L., et al.
Publicado: (2020) -
Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye
por: Pham, Thang L., et al.
Publicado: (2020) -
Defining a mechanistic link between pigment epithelium–derived factor, docosahexaenoic acid, and corneal nerve regeneration
por: Pham, Thang Luong, et al.
Publicado: (2017) -
ELV-N32 and RvD6 isomer decrease pro-inflammatory cytokines, senescence programming, ACE2 and SARS-CoV-2-spike protein RBD binding in injured cornea
por: Pham, Thang L., et al.
Publicado: (2021) -
Mouse strains and sexual divergence in corneal innervation and nerve regeneration
por: Pham, Thang Luong, et al.
Publicado: (2019)