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Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis
Can green chemistry be the right reading key to let organocatalyst design take a step forward towards sustainable catalysis? What if the intriguing chemistry promoted by more engineered organocatalysts was carried on by using renewable and naturally occurring molecular scaffolds, or at least synthet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362219/ https://www.ncbi.nlm.nih.gov/pubmed/33984187 http://dx.doi.org/10.1002/cssc.202100573 |
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author | Antenucci, Achille Dughera, Stefano Renzi, Polyssena |
author_facet | Antenucci, Achille Dughera, Stefano Renzi, Polyssena |
author_sort | Antenucci, Achille |
collection | PubMed |
description | Can green chemistry be the right reading key to let organocatalyst design take a step forward towards sustainable catalysis? What if the intriguing chemistry promoted by more engineered organocatalysts was carried on by using renewable and naturally occurring molecular scaffolds, or at least synthetic catalysts more respectful towards the principles of green chemistry? Within the frame of these questions, this Review will tackle the most commonly occurring organic chiral catalysts from the perspective of their synthesis rather than their employment in chemical methodologies or processes. A classification of the catalyst scaffolds based on their E factor will be provided, and the global E factor (E (G) factor) will be proposed as a new green chemistry metric to consider, also, the synthetic route to the catalyst within a given organocatalytic process. |
format | Online Article Text |
id | pubmed-8362219 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83622192021-08-17 Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis Antenucci, Achille Dughera, Stefano Renzi, Polyssena ChemSusChem Reviews Can green chemistry be the right reading key to let organocatalyst design take a step forward towards sustainable catalysis? What if the intriguing chemistry promoted by more engineered organocatalysts was carried on by using renewable and naturally occurring molecular scaffolds, or at least synthetic catalysts more respectful towards the principles of green chemistry? Within the frame of these questions, this Review will tackle the most commonly occurring organic chiral catalysts from the perspective of their synthesis rather than their employment in chemical methodologies or processes. A classification of the catalyst scaffolds based on their E factor will be provided, and the global E factor (E (G) factor) will be proposed as a new green chemistry metric to consider, also, the synthetic route to the catalyst within a given organocatalytic process. John Wiley and Sons Inc. 2021-06-23 2021-07-22 /pmc/articles/PMC8362219/ /pubmed/33984187 http://dx.doi.org/10.1002/cssc.202100573 Text en © 2021 The Authors. ChemSusChem published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Antenucci, Achille Dughera, Stefano Renzi, Polyssena Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title | Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title_full | Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title_fullStr | Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title_full_unstemmed | Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title_short | Green Chemistry Meets Asymmetric Organocatalysis: A Critical Overview on Catalysts Synthesis |
title_sort | green chemistry meets asymmetric organocatalysis: a critical overview on catalysts synthesis |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362219/ https://www.ncbi.nlm.nih.gov/pubmed/33984187 http://dx.doi.org/10.1002/cssc.202100573 |
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