Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature

BACKGROUND: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is relatively common in several cancers, such as small cell lung cancer. However, nedaplatin-induced SIADH is rare. We describe a case of SIADH mediated by nedaplatin. CASE SUMMARY: A 54-year-old female with nasopharynge...

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Detalles Bibliográficos
Autores principales: Tian, Lei, He, Li-Ya, Zhang, Hong-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362524/
https://www.ncbi.nlm.nih.gov/pubmed/34447829
http://dx.doi.org/10.12998/wjcc.v9.i23.6810
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author Tian, Lei
He, Li-Ya
Zhang, Hong-Zhen
author_facet Tian, Lei
He, Li-Ya
Zhang, Hong-Zhen
author_sort Tian, Lei
collection PubMed
description BACKGROUND: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is relatively common in several cancers, such as small cell lung cancer. However, nedaplatin-induced SIADH is rare. We describe a case of SIADH mediated by nedaplatin. CASE SUMMARY: A 54-year-old female with nasopharyngeal carcinoma was treated with nedaplatin and developed severe hyponatremia due to SIADH. The side effects were successfully treated by fluid restriction and sodium supplementation. CONCLUSION: This case report highlights the importance of cautiously treating life-threatening hyponatremia in patients treated with nedaplatin.
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spelling pubmed-83625242021-08-25 Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature Tian, Lei He, Li-Ya Zhang, Hong-Zhen World J Clin Cases Case Report BACKGROUND: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is relatively common in several cancers, such as small cell lung cancer. However, nedaplatin-induced SIADH is rare. We describe a case of SIADH mediated by nedaplatin. CASE SUMMARY: A 54-year-old female with nasopharyngeal carcinoma was treated with nedaplatin and developed severe hyponatremia due to SIADH. The side effects were successfully treated by fluid restriction and sodium supplementation. CONCLUSION: This case report highlights the importance of cautiously treating life-threatening hyponatremia in patients treated with nedaplatin. Baishideng Publishing Group Inc 2021-08-16 2021-08-16 /pmc/articles/PMC8362524/ /pubmed/34447829 http://dx.doi.org/10.12998/wjcc.v9.i23.6810 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Tian, Lei
He, Li-Ya
Zhang, Hong-Zhen
Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title_full Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title_fullStr Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title_full_unstemmed Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title_short Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
title_sort nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362524/
https://www.ncbi.nlm.nih.gov/pubmed/34447829
http://dx.doi.org/10.12998/wjcc.v9.i23.6810
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