Cargando…
Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature
BACKGROUND: Endometrial stromal tumors originate from the endometrial stroma and account for < 2% of all uterine tumors. Uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare histological class of endometrial stromal and related tumors according to the latest World Health Organiz...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362530/ https://www.ncbi.nlm.nih.gov/pubmed/34447841 http://dx.doi.org/10.12998/wjcc.v9.i23.6907 |
_version_ | 1783738182901170176 |
---|---|
author | Zhou, Fang-Fang He, Ying-Tao Li, Ying Zhang, Min Chen, Fang-Hong |
author_facet | Zhou, Fang-Fang He, Ying-Tao Li, Ying Zhang, Min Chen, Fang-Hong |
author_sort | Zhou, Fang-Fang |
collection | PubMed |
description | BACKGROUND: Endometrial stromal tumors originate from the endometrial stroma and account for < 2% of all uterine tumors. Uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare histological class of endometrial stromal and related tumors according to the latest World Health Organization classification of female genital tumors. Here, we report a case of UTROSCT in a 51-year-old woman. CASE SUMMARY: A 51-year-old woman had irregular menses for 6 mo. The patient visited a local hospital for vaginal bleeding. Pelvic computed tomography (CT) showed a mass in the pelvic cavity. Five days later, she came to our hospital for further diagnosis. The results of contrast-enhanced CT and pelvic ultrasound at our hospital suggested a malignant pelvic tumor. She then underwent total removal of the uterus with bilateral salpingectomy. Postoperative histological examination showed that the tumor cells had abundant cytoplasm, ovoid and spindle-shaped nuclei, fine chromatin, a high nucleoplasm ratio, and a lamellar distribution. The findings were consistent with UTROSCT, and the results of immunohistochemical analysis supported that diagnosis. The tumor was International Federation of Gynecology and Obstetrics stage IB. No adjuvant therapy was administered after radical surgery. The patient was followed up for 58 mo, and no recurrence was found. CONCLUSION: We report a case of UTROSCT with abnormal menstruation as a symptom, which is one of the most common symptoms. In patients with vaginal bleeding, ultrasonography can be used as a screening test because of its convenience, speed, and lack of radiation exposure. For patients with long-term tamoxifen use, routine monitoring of the endometrium is recommended. As UTROSCT may have low malignant potential, surgery remains the primary management strategy. Additionally, fertility preservation in patients of childbearing age is a vital consideration. |
format | Online Article Text |
id | pubmed-8362530 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-83625302021-08-25 Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature Zhou, Fang-Fang He, Ying-Tao Li, Ying Zhang, Min Chen, Fang-Hong World J Clin Cases Case Report BACKGROUND: Endometrial stromal tumors originate from the endometrial stroma and account for < 2% of all uterine tumors. Uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare histological class of endometrial stromal and related tumors according to the latest World Health Organization classification of female genital tumors. Here, we report a case of UTROSCT in a 51-year-old woman. CASE SUMMARY: A 51-year-old woman had irregular menses for 6 mo. The patient visited a local hospital for vaginal bleeding. Pelvic computed tomography (CT) showed a mass in the pelvic cavity. Five days later, she came to our hospital for further diagnosis. The results of contrast-enhanced CT and pelvic ultrasound at our hospital suggested a malignant pelvic tumor. She then underwent total removal of the uterus with bilateral salpingectomy. Postoperative histological examination showed that the tumor cells had abundant cytoplasm, ovoid and spindle-shaped nuclei, fine chromatin, a high nucleoplasm ratio, and a lamellar distribution. The findings were consistent with UTROSCT, and the results of immunohistochemical analysis supported that diagnosis. The tumor was International Federation of Gynecology and Obstetrics stage IB. No adjuvant therapy was administered after radical surgery. The patient was followed up for 58 mo, and no recurrence was found. CONCLUSION: We report a case of UTROSCT with abnormal menstruation as a symptom, which is one of the most common symptoms. In patients with vaginal bleeding, ultrasonography can be used as a screening test because of its convenience, speed, and lack of radiation exposure. For patients with long-term tamoxifen use, routine monitoring of the endometrium is recommended. As UTROSCT may have low malignant potential, surgery remains the primary management strategy. Additionally, fertility preservation in patients of childbearing age is a vital consideration. Baishideng Publishing Group Inc 2021-08-16 2021-08-16 /pmc/articles/PMC8362530/ /pubmed/34447841 http://dx.doi.org/10.12998/wjcc.v9.i23.6907 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Case Report Zhou, Fang-Fang He, Ying-Tao Li, Ying Zhang, Min Chen, Fang-Hong Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title | Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title_full | Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title_fullStr | Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title_full_unstemmed | Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title_short | Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature |
title_sort | uterine tumor resembling an ovarian sex cord tumor: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362530/ https://www.ncbi.nlm.nih.gov/pubmed/34447841 http://dx.doi.org/10.12998/wjcc.v9.i23.6907 |
work_keys_str_mv | AT zhoufangfang uterinetumorresemblinganovariansexcordtumoracasereportandreviewofliterature AT heyingtao uterinetumorresemblinganovariansexcordtumoracasereportandreviewofliterature AT liying uterinetumorresemblinganovariansexcordtumoracasereportandreviewofliterature AT zhangmin uterinetumorresemblinganovariansexcordtumoracasereportandreviewofliterature AT chenfanghong uterinetumorresemblinganovariansexcordtumoracasereportandreviewofliterature |