Six-Month In Vivo Safety Profiling of Topical Ocular AVV5–Decorin Gene Transfer

PURPOSE: A significant remission of corneal fibrosis and neovascularization in rabbit eye in vivo was observed from a tissue-selective localized adeno-associated virus (AAV)5–Decorin (Dcn) gene therapy. This study sought to investigate 6-month toxicity profiling of this gene therapy for the eye in v...

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Detalles Bibliográficos
Autores principales: Mohan, Rajiv R., Balne, Praveen K., Muayad, Maryam S., Tripathi, Ratnakar, Sinha, Nishant R., Gupta, Suneel, An, Jella A., Sinha, Prashant R., Hesemann, Nathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362634/
https://www.ncbi.nlm.nih.gov/pubmed/34383877
http://dx.doi.org/10.1167/tvst.10.10.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362634/
https://www.ncbi.nlm.nih.gov/pubmed/34383877
http://dx.doi.org/10.1167/tvst.10.10.5

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