Cellular and Behavioral Characterization of Pcdh19 Mutant Mice: subtle Molecular Changes, Increased Exploratory Behavior and an Impact of Social Environment

Mutations in the X-linked cell adhesion protein PCDH19 lead to seizures, cognitive impairment, and other behavioral comorbidities when present in a mosaic pattern. Neither the molecular mechanisms underpinning this disorder nor the function of PCDH19 itself are well understood. By combining RNA in s...

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Detalles Bibliográficos
Autores principales: Galindo-Riera, Natalia, Newbold, Sylvia Adriana, Sledziowska, Monika, Llinares-Benadero, Cristina, Griffiths, Jessica, Mire, Erik, Martinez-Garay, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362684/
https://www.ncbi.nlm.nih.gov/pubmed/34272258
http://dx.doi.org/10.1523/ENEURO.0510-20.2021

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