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A Genome-Scale CRISPR Knock-Out Screen Identifies MicroRNA-5197-5p as a Promising Radiosensitive Biomarker in Colorectal Cancer

Radioresistance is one of the main reasons causing unsatisfactory curative effects of ionizing radiation (IR) against colorectal cancer (CRC). However, its underlying mechanisms remain unclear yet. In the present study, we applied a genome-scale CRISPR knockout screen in combination of NGS sequencin...

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Detalles Bibliográficos
Autores principales:	Yu, Shijun, Li, Li, Fan, Kailing, Li, Yandong, Gao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362832/ https://www.ncbi.nlm.nih.gov/pubmed/34395263 http://dx.doi.org/10.3389/fonc.2021.696713

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