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Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension

Purpose To investigate any possible relationship between the central corneal thickness and the radial peripapillary capillary density detected by optical coherence tomography (OCT) angiography in eyes with ocular hypertension. Materials and methods In this observational study, 135 eyes were examined...

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Autores principales: Kollia, Elpida, Patsea, Eleni, Georgalas, Ilias, Brouzas, Dimitrios, Papaconstantinou, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362868/
https://www.ncbi.nlm.nih.gov/pubmed/34408962
http://dx.doi.org/10.7759/cureus.17138
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author Kollia, Elpida
Patsea, Eleni
Georgalas, Ilias
Brouzas, Dimitrios
Papaconstantinou, Dimitrios
author_facet Kollia, Elpida
Patsea, Eleni
Georgalas, Ilias
Brouzas, Dimitrios
Papaconstantinou, Dimitrios
author_sort Kollia, Elpida
collection PubMed
description Purpose To investigate any possible relationship between the central corneal thickness and the radial peripapillary capillary density detected by optical coherence tomography (OCT) angiography in eyes with ocular hypertension. Materials and methods In this observational study, 135 eyes were examined. OCT angiography of the optic disc (4.5 mm) and ultrasound corneal pachymetry were performed in all cases. Age, medical treatment for ocular hypertension, sex, and retinal nerve fiber layer thickness were evaluated. The main indices of blood flow were also examined. Spearman correlation coefficients were used to explore the association between two continuous variables. Results A directly proportional significance regarding the correlation between central corneal thickness and radial peripapillary network was indicated in eyes with ocular hypertension (p = .036). Conclusions Central corneal thickness and radial peripapillary capillary density constitute two essential screening parameters for patients with ocular hypertension.
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spelling pubmed-83628682021-08-17 Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension Kollia, Elpida Patsea, Eleni Georgalas, Ilias Brouzas, Dimitrios Papaconstantinou, Dimitrios Cureus Ophthalmology Purpose To investigate any possible relationship between the central corneal thickness and the radial peripapillary capillary density detected by optical coherence tomography (OCT) angiography in eyes with ocular hypertension. Materials and methods In this observational study, 135 eyes were examined. OCT angiography of the optic disc (4.5 mm) and ultrasound corneal pachymetry were performed in all cases. Age, medical treatment for ocular hypertension, sex, and retinal nerve fiber layer thickness were evaluated. The main indices of blood flow were also examined. Spearman correlation coefficients were used to explore the association between two continuous variables. Results A directly proportional significance regarding the correlation between central corneal thickness and radial peripapillary network was indicated in eyes with ocular hypertension (p = .036). Conclusions Central corneal thickness and radial peripapillary capillary density constitute two essential screening parameters for patients with ocular hypertension. Cureus 2021-08-12 /pmc/articles/PMC8362868/ /pubmed/34408962 http://dx.doi.org/10.7759/cureus.17138 Text en Copyright © 2021, Kollia et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Kollia, Elpida
Patsea, Eleni
Georgalas, Ilias
Brouzas, Dimitrios
Papaconstantinou, Dimitrios
Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title_full Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title_fullStr Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title_full_unstemmed Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title_short Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension
title_sort correlation between central corneal thickness and radial peripapillary capillary density, in patients with ocular hypertension
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362868/
https://www.ncbi.nlm.nih.gov/pubmed/34408962
http://dx.doi.org/10.7759/cureus.17138
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