Clinical Relevance of Mallampati Grading in Predicting Difficult Intubation in the Era of Various New Clinical Predictors

Background and aims Management of difficult airway can be associated with serious morbidity and mortality and it is a basic and serious concern for anesthesiologists. The preoperative airway assessment is done by using conventional clinical predictors. The present study was conducted to find the correlation of various new clinical predictors with the Cormack-Lehane (CL) grade at the laryngoscopic view in patients undergoing general anesthesia with endotracheal intubation. Settings and design The prospective, comparative, observational, double-blind study was carried at Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow. Materials and methods The study was conducted in 150 patients undergoing elective surgery under general anaesthesia. The primary outcome was the measurement of clinical airway assessment preoperatively based on certain parameters (inter incisor gap (IIG), modified Mallampati grading (MPG), neck circumference/thyromental distance (NC/TMD), ratio of height to thyromental distance (RHTMD)). The secondary outcome was the correlation of clinical airway assessment with CL grading to predict difficult intubation. The sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) of the parameters were assessed. Statistical analysis The association between different predictors and difficult laryngoscopy was evaluated using binary univariate logistic regression and multivariate logistic regression and the significant clinical predictors were assessed by using Pearson’s correlation. A p-value of < 0.05 was considered significant. Results The incidence of difficult intubation in this study was 13.3%. Among the clinical predictors, the Mallampati grading has the maximum receiver operating characteristic (ROC) and area under the curve (AUC) with 86.7 % sensitivity to predict difficult laryngoscopy followed by NC/TMD and body mass index. Conclusion Modified Mallampati grading still holds its significant value among new predictors in the assessment of difficult laryngoscopy.