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Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362882/ https://www.ncbi.nlm.nih.gov/pubmed/34395558 http://dx.doi.org/10.3389/fcvm.2021.688351 |
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author | Bergonti, Marco Ascione, Ciro Agostoni, Piergiuseppe Castelli, Roberto Vignati, Carlo |
author_facet | Bergonti, Marco Ascione, Ciro Agostoni, Piergiuseppe Castelli, Roberto Vignati, Carlo |
author_sort | Bergonti, Marco |
collection | PubMed |
description | Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases are frequently associated with a high risk of thromboembolism, CMML is often accompanied by immune-mediated hemorrhagic diathesis. Indeed, very few reports in literature report thrombotic complications of CMML patients. We will briefly present here the case of a patient with CMML who developed a massive right atrial thrombus. We aim to highlight the non-negligible thrombotic burden of the disease, and we will get through the differential diagnosis of right atrial masses and the management of right atrial thrombi, which are a rare and poorly known entity. |
format | Online Article Text |
id | pubmed-8362882 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83628822021-08-14 Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report Bergonti, Marco Ascione, Ciro Agostoni, Piergiuseppe Castelli, Roberto Vignati, Carlo Front Cardiovasc Med Cardiovascular Medicine Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases are frequently associated with a high risk of thromboembolism, CMML is often accompanied by immune-mediated hemorrhagic diathesis. Indeed, very few reports in literature report thrombotic complications of CMML patients. We will briefly present here the case of a patient with CMML who developed a massive right atrial thrombus. We aim to highlight the non-negligible thrombotic burden of the disease, and we will get through the differential diagnosis of right atrial masses and the management of right atrial thrombi, which are a rare and poorly known entity. Frontiers Media S.A. 2021-07-30 /pmc/articles/PMC8362882/ /pubmed/34395558 http://dx.doi.org/10.3389/fcvm.2021.688351 Text en Copyright © 2021 Bergonti, Ascione, Agostoni, Castelli and Vignati. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Bergonti, Marco Ascione, Ciro Agostoni, Piergiuseppe Castelli, Roberto Vignati, Carlo Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title | Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title_full | Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title_fullStr | Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title_full_unstemmed | Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title_short | Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report |
title_sort | massive right atrial thrombosis: are you brave enough to start anticoagulation? a case report |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362882/ https://www.ncbi.nlm.nih.gov/pubmed/34395558 http://dx.doi.org/10.3389/fcvm.2021.688351 |
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