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Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases...

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Autores principales: Bergonti, Marco, Ascione, Ciro, Agostoni, Piergiuseppe, Castelli, Roberto, Vignati, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362882/
https://www.ncbi.nlm.nih.gov/pubmed/34395558
http://dx.doi.org/10.3389/fcvm.2021.688351
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author Bergonti, Marco
Ascione, Ciro
Agostoni, Piergiuseppe
Castelli, Roberto
Vignati, Carlo
author_facet Bergonti, Marco
Ascione, Ciro
Agostoni, Piergiuseppe
Castelli, Roberto
Vignati, Carlo
author_sort Bergonti, Marco
collection PubMed
description Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases are frequently associated with a high risk of thromboembolism, CMML is often accompanied by immune-mediated hemorrhagic diathesis. Indeed, very few reports in literature report thrombotic complications of CMML patients. We will briefly present here the case of a patient with CMML who developed a massive right atrial thrombus. We aim to highlight the non-negligible thrombotic burden of the disease, and we will get through the differential diagnosis of right atrial masses and the management of right atrial thrombi, which are a rare and poorly known entity.
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spelling pubmed-83628822021-08-14 Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report Bergonti, Marco Ascione, Ciro Agostoni, Piergiuseppe Castelli, Roberto Vignati, Carlo Front Cardiovasc Med Cardiovascular Medicine Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping myelodysplastic and myeloproliferative features. The disease is generally characterized by blood monocytosis, bone marrow dysplasia, cytopenia, and hepatosplenomegaly. While malignant blood diseases are frequently associated with a high risk of thromboembolism, CMML is often accompanied by immune-mediated hemorrhagic diathesis. Indeed, very few reports in literature report thrombotic complications of CMML patients. We will briefly present here the case of a patient with CMML who developed a massive right atrial thrombus. We aim to highlight the non-negligible thrombotic burden of the disease, and we will get through the differential diagnosis of right atrial masses and the management of right atrial thrombi, which are a rare and poorly known entity. Frontiers Media S.A. 2021-07-30 /pmc/articles/PMC8362882/ /pubmed/34395558 http://dx.doi.org/10.3389/fcvm.2021.688351 Text en Copyright © 2021 Bergonti, Ascione, Agostoni, Castelli and Vignati. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Bergonti, Marco
Ascione, Ciro
Agostoni, Piergiuseppe
Castelli, Roberto
Vignati, Carlo
Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title_full Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title_fullStr Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title_full_unstemmed Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title_short Massive Right Atrial Thrombosis: Are You Brave Enough to Start Anticoagulation? A Case Report
title_sort massive right atrial thrombosis: are you brave enough to start anticoagulation? a case report
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362882/
https://www.ncbi.nlm.nih.gov/pubmed/34395558
http://dx.doi.org/10.3389/fcvm.2021.688351
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