Using de novo assembly to identify structural variation of eight complex immune system gene regions

Driven by the necessity to survive environmental pathogens, the human immune system has evolved exceptional diversity and plasticity, to which several factors contribute including inheritable structural polymorphism of the underlying genes. Characterizing this variation is challenging due to the com...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Yuan, Roberts, Hannah, Flores, David S. C., Cutler, Antony J., Brown, Andrew C., Whalley, Justin P., Mielczarek, Olga, Buck, David, Lockstone, Helen, Xella, Barbara, Oliver, Karen, Corton, Craig, Betteridge, Emma, Bashford-Rogers, Rachael, Knight, Julian C., Todd, John A., Band, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363018/
https://www.ncbi.nlm.nih.gov/pubmed/34343164
http://dx.doi.org/10.1371/journal.pcbi.1009254

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