ZEB2 facilitates peritoneal metastasis by regulating the invasiveness and tumorigenesis of cancer stem-like cells in high-grade serous ovarian cancers

Peritoneal metastasis is a common issue in the progression of high-grade serous ovarian cancers (HGSOCs), yet the underlying mechanism remains unconfirmed. We demonstrated that ZEB2, the transcription factor of epithelial–mesenchymal transition (EMT), was upregulated in ascites cells from HGSOC pati...

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Detalles Bibliográficos
Autores principales: Li, Yiying, Fei, He, Lin, Qiwang, Liang, Fan, You, Yanan, Li, Ming, Wu, Mengyao, Qu, Ying, Li, Pengfei, Yuan, Yan, Chen, Tong, Jiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363099/
https://www.ncbi.nlm.nih.gov/pubmed/34211089
http://dx.doi.org/10.1038/s41388-021-01913-3

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