Cargando…

The Evolution of Single-Cell Analysis and Utility in Drug Development

This review provides a brief history of the advances of cellular analysis tools focusing on instrumentation, detection probes, and data analysis tools. The interplay of technological advancement and a deeper understanding of cellular biology are emphasized. The relevance of this topic to drug develo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mitra-Kaushik, Shibani, Mehta-Damani, Anita, Stewart, Jennifer J., Green, Cherie, Litwin, Virginia, Gonneau, Christèle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363238/ https://www.ncbi.nlm.nih.gov/pubmed/34389904 http://dx.doi.org/10.1208/s12248-021-00633-6

Ejemplares similares

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells
por: Souilhol, Céline, et al.
Publicado: (2016)

Utility of Reactive Species Generation in Plasma Medicine for Neuronal Development
por: Mitra, Sarmistha, et al.
Publicado: (2020)

Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
por: Claudinot, Stéphanie, et al.
Publicado: (2020)

Fluorescent tags to explore cell wall structure and dynamics
por: Gonneau, Martine, et al.
Publicado: (2012)

Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users
por: Kirk, Gregory D., et al.
Publicado: (2017)

O022: Development of an electronic dashboard to assist surveillance
por: Wallace, S, et al.
Publicado: (2013)

Cell wall integrity signaling in plants: Malectin-domain kinases and lessons from other kingdoms
por: Doblas, Verónica G., et al.
Publicado: (2018)

Uptake and Acceptability of Information and Communication Technology in a Community-Based Cohort of People Who Inject Drugs: Implications for Mobile Health Interventions
por: Genz, Andrew, et al.
Publicado: (2015)

Evolution and intelligent design in drug development
por: Agafonov, Roman V., et al.
Publicado: (2015)

T-Cell Dependent Immunogenicity of Protein Therapeutics Pre-clinical Assessment and Mitigation–Updated Consensus and Review 2020
por: Jawa, Vibha, et al.
Publicado: (2020)

Frailty, HIV Infection, and Mortality in an Aging Cohort of Injection Drug Users
por: Piggott, Damani A., et al.
Publicado: (2013)

Developing a well-received pre-matriculation program: the evolution of MedFIT
por: Allen, Alexa, et al.
Publicado: (2022)

Reducing injection intensity is associated with decreased risk for invasive bacterial infection among high-frequency injection drug users
por: Islam, Salequl, et al.
Publicado: (2019)

Developing evolution-resistant drugs for COVID-19
por: Weinreich, Daniel M
Publicado: (2022)

Evolution of selenium utilization traits
por: Romero, Héctor, et al.
Publicado: (2005)

Reviving the Autopsy for Modern Cancer Evolution Research
por: Robb, Tamsin Joy, et al.
Publicado: (2021)

The health and social consequences during the initial period of the COVID-19 pandemic among current and former people who inject drugs: A rapid phone survey in Baltimore, Maryland
por: Genberg, Becky L., et al.
Publicado: (2021)

THE GENETIC CONTROL OF γ-GLOBULIN HEAVY CHAINS : STUDIES OF THE MAJOR HEAVY CHAIN SUBGROUP UTILIZING MULTIPLE GENETIC MARKERS
por: Litwin, Stephen D., et al.
Publicado: (1967)

Utilization and Monetization of Healthcare Data in Developing Countries
por: Bram, Joshua T., et al.
Publicado: (2015)

Evolution of isolated systolic hypertension with normal central blood pressure in adolescents—prospective study
por: Obrycki, Łukasz, et al.
Publicado: (2020)

The Developing Utility of Zebrafish Models for Cognitive Enhancers Research
por: Stewart, Adam Michael, et al.
Publicado: (2012)

Evolution of non-expected utility preferences
por: Widekind, Sven von, et al.
Publicado: (2008)

Utilizing graph machine learning within drug discovery and development
por: Gaudelet, Thomas, et al.
Publicado: (2021)

Unification by Fiat: Arrested Development of Predictive Processing
por: Litwin, Piotr, et al.
Publicado: (2020)

The Times They Are A-Changin’: Heterochrony in Plant Development and Evolution
por: Buendía-Monreal, Manuel, et al.
Publicado: (2018)

Perspective on Data‐Sharing Requirements for the Necessary Evolution of Drug Development
por: Barrett, Jeffrey S.
Publicado: (2020)

Single-cell transcriptomics unveils xylem cell development and evolution
por: Tung, Chia-Chun, et al.
Publicado: (2023)

Prognostic utility of cardiovascular indices in COVID-19 infection: A single-center prospective study in India
por: Lakhani, Aisha, et al.
Publicado: (2022)

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development
por: Prior, Helen, et al.
Publicado: (2018)

Breaking the Bottleneck in Anticancer Drug Development: Efficient Utilization of Synthetic Biology
por: Wang, Haibo, et al.
Publicado: (2022)

Utilization of the Mating Scaffold Protein in the Evolution of a New Signal Transduction Pathway for Biofilm Development
por: Yi, Song, et al.
Publicado: (2011)

PLATELET COUNT IN WOMEN WITH PREGNANCY INDUCED HYPERTENSION IN UNIVERSITY HOSPITAL CENTER OF MOTHER AND CHILD HEALTHCARE “KOçO GLIOZHENI”, TIRANA, ALBANIA
por: Damani, Zamir
Publicado: (2016)

A brief history of acute stroke care
por: Damani, Rahul
Publicado: (2018)

DISSEMINATED INTRAVASCULAR COAGULOPATHY FROM WARM AUTOIMMUNE HEMOLYTIC ANEMIA IN A PATIENT WITH COVID-19
por: Damani, Jalal
Publicado: (2020)

Communicable Disease Control Handbook second edition
por: Damani, Nizam
Publicado: (2006)

COVID-19-ASSOCIATED PULMONARY FUSARIUM INFECTION IN A NON-CRITICALLY ILL IMMUNOCOMPETANT PATIENT
por: DAMANI, JALAL
Publicado: (2021)

Changes in Drug Utilization After Publication of Clinical Trials and Drug-Related Scandals in Japan: An Interrupted Time Series Analysis, 2005–2017
por: Fukuma, Shingo, et al.
Publicado: (2021)

The utility of physiotherapy assessments delivered by telehealth: A systematic review
por: Zischke, Cherie, et al.
Publicado: (2021)

Impact of the Drug Prices Control Order (2013) on the Utilization of Anticancer Medicines in India: An Interrupted Time-Series Analysis
por: Sharma, Bhavna, et al.
Publicado: (2022)

Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes
por: Menendez-Montes, Ivan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mrpkd95no0b0alu34lkvsc1t5n