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Colonic Epithelial PHLPP2 Deficiency Promotes Colonic Epithelial Pyroptosis by Activating the NF-κB Signaling Pathway

BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disease with increasing prevalence worldwide. Barrier defect in intestinal epithelial cells (IECs) is one of the main pathogeneses in UC. Pyroptosis is a programmed lytic cell death and is triggered by inflammatory caspases, while little...

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Detalles Bibliográficos
Autores principales:	Li, De-feng, Chang, Xin, Zhao, Jiu-long, Chen, Xuan-min, Xu, Zheng-lei, Zhang, Ding-guo, Wu, Ben-hua, Wang, Li-sheng, Bai, Yu, Yao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363454/ https://www.ncbi.nlm.nih.gov/pubmed/34394827 http://dx.doi.org/10.1155/2021/5570731

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