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Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality

Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite generated from its dietary precursors such as choline, has been identified as an independent risk factor for atherosclerosis. Metformin is the most widely used drug for the treatment of type 2 diabetes (T2D), which has therapeutic...

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Detalles Bibliográficos
Autores principales: Su, Chunyan, Li, Xingxing, Yang, Yuxin, Du, Yu, Zhang, Xiumin, Wang, Li, Hong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363624/
https://www.ncbi.nlm.nih.gov/pubmed/34389700
http://dx.doi.org/10.1038/s41387-021-00169-w

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