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Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence

Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. The two predominant histologic variants of RMS, embryonal and alveolar rhabdomyosarcoma (eRMS and aRMS, respectively), carry very different prognoses. While eRMS is associated with an intermediate prognosis, the 5-year survival...

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Detalles Bibliográficos
Autores principales: Li, Jenny J., Kovach, Alexander R., DeMonia, Margaret, Slemmons, Katherine K., Oristian, Kristianne M., Chen, Candy, Linardic, Corinne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363632/
https://www.ncbi.nlm.nih.gov/pubmed/34389744
http://dx.doi.org/10.1038/s41598-021-95355-2