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Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence
Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. The two predominant histologic variants of RMS, embryonal and alveolar rhabdomyosarcoma (eRMS and aRMS, respectively), carry very different prognoses. While eRMS is associated with an intermediate prognosis, the 5-year survival...
Autores principales: | Li, Jenny J., Kovach, Alexander R., DeMonia, Margaret, Slemmons, Katherine K., Oristian, Kristianne M., Chen, Candy, Linardic, Corinne M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363632/ https://www.ncbi.nlm.nih.gov/pubmed/34389744 http://dx.doi.org/10.1038/s41598-021-95355-2 |
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