The pathogenesis of mesothelioma is driven by a dysregulated translatome

Malignant mesothelioma (MpM) is an aggressive, invariably fatal tumour that is causally linked with asbestos exposure. The disease primarily results from loss of tumour suppressor gene function and there are no ‘druggable’ driver oncogenes associated with MpM. To identify opportunities for managemen...

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Detalles Bibliográficos
Autores principales: Grosso, Stefano, Marini, Alberto, Gyuraszova, Katarina, Voorde, Johan Vande, Sfakianos, Aristeidis, Garland, Gavin D., Tenor, Angela Rubio, Mordue, Ryan, Chernova, Tanya, Morone, Nobu, Sereno, Marco, Smith, Claire P., Officer, Leah, Farahmand, Pooyeh, Rooney, Claire, Sumpton, David, Das, Madhumita, Teodósio, Ana, Ficken, Catherine, Martin, Maria Guerra, Spriggs, Ruth V., Sun, Xiao-Ming, Bushell, Martin, Sansom, Owen J., Murphy, Daniel, MacFarlane, Marion, Le Quesne, John P. C., Willis, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363647/
https://www.ncbi.nlm.nih.gov/pubmed/34389715
http://dx.doi.org/10.1038/s41467-021-25173-7

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