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Donor genetic variants in interleukin-6 and interleukin-6 receptor associate with biopsy-proven rejection following kidney transplantation

Rejection after kidney transplantation remains an important cause of allograft failure that markedly impacts morbidity. Cytokines are a major player in rejection, and we, therefore, explored the impact of interleukin-6 (IL6) and IL-6 receptor (IL6R) gene polymorphisms on the occurrence of rejection...

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Detalles Bibliográficos
Autores principales: Poppelaars, Felix, Gaya da Costa, Mariana, Eskandari, Siawosh K., Damman, Jeffrey, Seelen, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363661/
https://www.ncbi.nlm.nih.gov/pubmed/34389747
http://dx.doi.org/10.1038/s41598-021-95714-z