Mapping the biosynthetic pathway of a hybrid polyketide-nonribosomal peptide in a metazoan

Polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid systems typically use complex protein-protein interactions to facilitate direct transfer of intermediates between these multimodular megaenzymes. In the canal-associated neurons (CANs) of Caenorhabditis elegans, PKS-1 and NR...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Likui, Gordon, Matthew T., Liu, Ying, Basso, Kari B., Butcher, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363725/
https://www.ncbi.nlm.nih.gov/pubmed/34389721
http://dx.doi.org/10.1038/s41467-021-24682-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363725/
https://www.ncbi.nlm.nih.gov/pubmed/34389721
http://dx.doi.org/10.1038/s41467-021-24682-9

Ejemplares similares