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Mapping the biosynthetic pathway of a hybrid polyketide-nonribosomal peptide in a metazoan

Polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid systems typically use complex protein-protein interactions to facilitate direct transfer of intermediates between these multimodular megaenzymes. In the canal-associated neurons (CANs) of Caenorhabditis elegans, PKS-1 and NR...

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Detalles Bibliográficos
Autores principales:	Feng, Likui, Gordon, Matthew T., Liu, Ying, Basso, Kari B., Butcher, Rebecca A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363725/ https://www.ncbi.nlm.nih.gov/pubmed/34389721 http://dx.doi.org/10.1038/s41467-021-24682-9

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