Severe Neurological Sequelae after a Recreational Dose of LSD

A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amoun...

Descripción completa

Detalles Bibliográficos
Autores principales: Aakerøy, Rachel, Brede, Wenche Rødseth, Stølen, Stian Bergseng, Krabseth, Hege-Merete, Michelsen, Lisbeth Solem, Andreassen, Trine Naalsund, Ader, Tiina, Frost, Joachim, Slettom, Grete, Steihaug, Ole Martin, Slørdal, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363806/
https://www.ncbi.nlm.nih.gov/pubmed/33031536
http://dx.doi.org/10.1093/jat/bkaa145
_version_ 1783738411832573952
author Aakerøy, Rachel
Brede, Wenche Rødseth
Stølen, Stian Bergseng
Krabseth, Hege-Merete
Michelsen, Lisbeth Solem
Andreassen, Trine Naalsund
Ader, Tiina
Frost, Joachim
Slettom, Grete
Steihaug, Ole Martin
Slørdal, Lars
author_facet Aakerøy, Rachel
Brede, Wenche Rødseth
Stølen, Stian Bergseng
Krabseth, Hege-Merete
Michelsen, Lisbeth Solem
Andreassen, Trine Naalsund
Ader, Tiina
Frost, Joachim
Slettom, Grete
Steihaug, Ole Martin
Slørdal, Lars
author_sort Aakerøy, Rachel
collection PubMed
description A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.
format Online
Article
Text
id pubmed-8363806
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-83638062021-08-17 Severe Neurological Sequelae after a Recreational Dose of LSD Aakerøy, Rachel Brede, Wenche Rødseth Stølen, Stian Bergseng Krabseth, Hege-Merete Michelsen, Lisbeth Solem Andreassen, Trine Naalsund Ader, Tiina Frost, Joachim Slettom, Grete Steihaug, Ole Martin Slørdal, Lars J Anal Toxicol Case Report A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals. Oxford University Press 2020-10-08 /pmc/articles/PMC8363806/ /pubmed/33031536 http://dx.doi.org/10.1093/jat/bkaa145 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Aakerøy, Rachel
Brede, Wenche Rødseth
Stølen, Stian Bergseng
Krabseth, Hege-Merete
Michelsen, Lisbeth Solem
Andreassen, Trine Naalsund
Ader, Tiina
Frost, Joachim
Slettom, Grete
Steihaug, Ole Martin
Slørdal, Lars
Severe Neurological Sequelae after a Recreational Dose of LSD
title Severe Neurological Sequelae after a Recreational Dose of LSD
title_full Severe Neurological Sequelae after a Recreational Dose of LSD
title_fullStr Severe Neurological Sequelae after a Recreational Dose of LSD
title_full_unstemmed Severe Neurological Sequelae after a Recreational Dose of LSD
title_short Severe Neurological Sequelae after a Recreational Dose of LSD
title_sort severe neurological sequelae after a recreational dose of lsd
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363806/
https://www.ncbi.nlm.nih.gov/pubmed/33031536
http://dx.doi.org/10.1093/jat/bkaa145
work_keys_str_mv AT aakerøyrachel severeneurologicalsequelaeafterarecreationaldoseoflsd
AT bredewencherødseth severeneurologicalsequelaeafterarecreationaldoseoflsd
AT stølenstianbergseng severeneurologicalsequelaeafterarecreationaldoseoflsd
AT krabsethhegemerete severeneurologicalsequelaeafterarecreationaldoseoflsd
AT michelsenlisbethsolem severeneurologicalsequelaeafterarecreationaldoseoflsd
AT andreassentrinenaalsund severeneurologicalsequelaeafterarecreationaldoseoflsd
AT adertiina severeneurologicalsequelaeafterarecreationaldoseoflsd
AT frostjoachim severeneurologicalsequelaeafterarecreationaldoseoflsd
AT slettomgrete severeneurologicalsequelaeafterarecreationaldoseoflsd
AT steihaugolemartin severeneurologicalsequelaeafterarecreationaldoseoflsd
AT slørdallars severeneurologicalsequelaeafterarecreationaldoseoflsd

Ejemplares similares