Novel molecular targeted therapies for patients with neurofibromatosis type 1 with inoperable plexiform neurofibromas: a comprehensive review

Neurofibromatosis type 1 (NF1) is a genetic disorder that carries a higher risk of tumor development. Plexiform neurofibromas (PNs) are present in 50% of NF1 and cause significant morbidity when surgery is not feasible. Systemic therapies had not succeeded to reduce PN tumor volume until 2016 when t...

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Detalles Bibliográficos
Autores principales: Solares, I., Viñal, D., Morales-Conejo, M., Rodriguez-Salas, N., Feliu, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363824/
https://www.ncbi.nlm.nih.gov/pubmed/34388689
http://dx.doi.org/10.1016/j.esmoop.2021.100223

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