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Structural basis for template switching by a group II intron–encoded non-LTR-retroelement reverse transcriptase

Reverse transcriptases (RTs) can switch template strands during complementary DNA synthesis, enabling them to join discontinuous nucleic acid sequences. Template switching (TS) plays crucial roles in retroviral replication and recombination, is used for adapter addition in RNA-Seq, and may contribut...

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Detalles Bibliográficos
Autores principales:	Lentzsch, Alfred M., Stamos, Jennifer L., Yao, Jun, Russell, Rick, Lambowitz, Alan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363836/ https://www.ncbi.nlm.nih.gov/pubmed/34280434 http://dx.doi.org/10.1016/j.jbc.2021.100971

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