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Phenothiazines alter plasma membrane properties and sensitize cancer cells to injury by inhibiting annexin-mediated repair

Repair of damaged plasma membrane in eukaryotic cells is largely dependent on the binding of annexin repair proteins to phospholipids. Changing the biophysical properties of the plasma membrane may provide means to compromise annexin-mediated repair and sensitize cells to injury. Since, cancer cells...

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Detalles Bibliográficos
Autores principales: Heitmann, Anne Sofie Busk, Zanjani, Ali Asghar Hakami, Klenow, Martin Berg, Mularski, Anna, Sønder, Stine Lauritzen, Lund, Frederik Wendelboe, Boye, Theresa Louise, Dias, Catarina, Bendix, Poul Martin, Simonsen, Adam Cohen, Khandelia, Himanshu, Nylandsted, Jesper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363839/
https://www.ncbi.nlm.nih.gov/pubmed/34324830
http://dx.doi.org/10.1016/j.jbc.2021.101012