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Phenothiazines alter plasma membrane properties and sensitize cancer cells to injury by inhibiting annexin-mediated repair
Repair of damaged plasma membrane in eukaryotic cells is largely dependent on the binding of annexin repair proteins to phospholipids. Changing the biophysical properties of the plasma membrane may provide means to compromise annexin-mediated repair and sensitize cells to injury. Since, cancer cells...
Autores principales: | Heitmann, Anne Sofie Busk, Zanjani, Ali Asghar Hakami, Klenow, Martin Berg, Mularski, Anna, Sønder, Stine Lauritzen, Lund, Frederik Wendelboe, Boye, Theresa Louise, Dias, Catarina, Bendix, Poul Martin, Simonsen, Adam Cohen, Khandelia, Himanshu, Nylandsted, Jesper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363839/ https://www.ncbi.nlm.nih.gov/pubmed/34324830 http://dx.doi.org/10.1016/j.jbc.2021.101012 |
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