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miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

OBJECTIVES: Restenosis after vessel angioplasty due to dedifferentiation of the vascular smooth muscle cells (VSMCs) limits the success of surgical treatment of vascular occlusions. Type 2 diabetes (T2DM) has a major impact on restenosis, with patients exhibiting more aggressive forms of vascular di...

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Detalles Bibliográficos
Autores principales: Arevalo-Martinez, Marycarmen, Cidad, Pilar, Moreno-Estar, Sara, Fernández, Mirella, Albinsson, Sebastian, Cózar-Castellano, Irene, López-López, José R., Pérez-Garcia, M. Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363881/
https://www.ncbi.nlm.nih.gov/pubmed/34298200
http://dx.doi.org/10.1016/j.molmet.2021.101306