Cargando…

Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles

Mesenchymal stromal cell‐derived extracellular vesicles (MSC‐EVs) turn out to be a promising source of cell‐free therapy. Here, we investigated the biodistribution and effect of nebulized human adipose‐derived MSC‐EVs (haMSC‐EVs) in the preclinical lung injury model and explored the safety of nebuli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Meng‐meng, Yang, Qing‐yuan, Monsel, Antoine, Yan, Jia‐yang, Dai, Cheng‐xiang, Zhao, Jing‐ya, Shi, Guo‐chao, Zhou, Min, Zhu, Xue‐mei, Li, Su‐ke, Li, Ping, Wang, Jing, Li, Meng, Lei, Ji‐gang, Xu, Dong, Zhu, Ying‐gang, Qu, Jie‐ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363910/ https://www.ncbi.nlm.nih.gov/pubmed/34429860 http://dx.doi.org/10.1002/jev2.12134

Ejemplares similares

Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study
por: Zhu, Ying-Gang, et al.
Publicado: (2022)

Role of miR‐466 in mesenchymal stromal cell derived extracellular vesicles treating inoculation pneumonia caused by multidrug‐resistant Pseudomonas aeruginosa
por: Shi, Meng‐meng, et al.
Publicado: (2021)

Inoculation Pneumonia Caused by Coagulase Negative Staphylococcus
por: Shi, Meng-meng, et al.
Publicado: (2019)

Nebulized Colistin in Ventilator-Associated Pneumonia and Tracheobronchitis: Historical Background, Pharmacokinetics and Perspectives
por: Zhu, Yinggang, et al.
Publicado: (2021)

Clinical safety and efficacy of allogenic human adipose mesenchymal stromal cells-derived exosomes in patients with mild to moderate Alzheimer’s disease: a phase I/II clinical trial
por: Xie, Xinyi, et al.
Publicado: (2023)

Preclinical Toxicity Evaluation of Clinical Grade Placenta-Derived Decidua Stromal Cells
por: Sadeghi, Behnam, et al.
Publicado: (2019)

Nebulized anticoagulants for acute lung injury - a systematic review of preclinical and clinical investigations
por: Tuinman, Pieter R, et al.
Publicado: (2012)

Survival outcomes of different treatment modalities in patients with low-grade endometrial stromal sarcoma
por: Wang, Ming, et al.
Publicado: (2019)

Mesh nebulizer is as effective as jet nebulizer in clinical practice of acute asthma in children
por: SOYER, Özge, et al.
Publicado: (2019)

GMP Compliant Production of a Cryopreserved Adipose-Derived Stromal Cell Product for Feasible and Allogeneic Clinical Use
por: Haack-Sørensen, Mandana, et al.
Publicado: (2022)

Subcutaneous Injection of Allogeneic Adipose-Derived Mesenchymal Stromal Cells in Psoriasis Plaques: Clinical Trial Phase I
por: Bajouri, Amir, et al.
Publicado: (2023)

Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations
por: Klyachko, Natalia L., et al.
Publicado: (2020)

Standard toxicity study of clinical-grade allogeneic human bone marrow-derived clonal mesenchymal stromal cells
por: Tayebi, Behnoosh, et al.
Publicado: (2022)

One repeated transplantation of allogeneic umbilical cord mesenchymal stromal cells in type 1 diabetes: an open parallel controlled clinical study
por: Lu, Jing, et al.
Publicado: (2021)

Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021
por: Wang, Chengshuo, et al.
Publicado: (2021)

Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus Monkeys
por: Jia, Jilei, et al.
Publicado: (2022)

Low grade epithelial stromal tumour of the seminal vesicle
por: Monica, Bruno, et al.
Publicado: (2008)

Mesenchymal stromal cell extracellular vesicles for multiple sclerosis in preclinical rodent models: A meta-analysis
por: Xun, Chengfeng, et al.
Publicado: (2022)

Multi-compositional MRI evaluation of repair cartilage in knee osteoarthritis with treatment of allogeneic human adipose-derived mesenchymal progenitor cells
por: Zhao, Xinxin, et al.
Publicado: (2019)

Editorial: Mesenchymal Stromal Cells: Preclinical and Clinical Challenges
por: Oliva, Joan, et al.
Publicado: (2022)

Bacterial Surface Detachment during Nebulization with Contaminated Reusable Home Nebulizers
por: Harris, Jamie C., et al.
Publicado: (2022)

Treatment of uterine high-grade endometrial stromal sarcoma with apatinib combined with chemotherapy: A case report
por: Zhang, Ying, et al.
Publicado: (2019)

Preclinical safety & toxicity evaluation of pooled, allogeneic human bone marrow-derived mesenchymal stromal cells
por: Rengasamy, Mathiyazhagan, et al.
Publicado: (2016)

Pooled Analysis of Mesenchymal Stromal Cell-Derived Extracellular Vesicle Therapy for Liver Disease in Preclinical Models
por: Fang, Xinru, et al.
Publicado: (2023)

Delayed Supplementation Strategy of Extracellular Vesicles from Adipose-Derived Mesenchymal Stromal Cells with Improved Proregenerative Efficiency in a Fat Transplantation Model
por: Mou, Shan, et al.
Publicado: (2022)

Mesenchymal stromal/stem cells and their extracellular vesicles in liver diseases: insights on their immunomodulatory roles and clinical applications
por: Huai, Qian, et al.
Publicado: (2023)

Clinical effects and pharmacokinetics of nebulized lidocaine in healthy horses
por: Minuto, Jillian, et al.
Publicado: (2022)

Liver governs adipose remodelling via extracellular vesicles in response to lipid overload
por: Zhao, Yue, et al.
Publicado: (2020)

Clinical applications of susceptibility-weighted imaging in detecting and grading intracranial gliomas: a review
por: Mohammed, Wasif, et al.
Publicado: (2013)

Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint
por: Gupta, Pawan Kumar, et al.
Publicado: (2016)

Perspectives for Clinical Translation of Adipose Stromal/Stem Cells
por: Patrikoski, Mimmi, et al.
Publicado: (2019)

Research Status in Clinical Practice Regarding Pediatric and Adolescent Bipolar Disorders
por: Liu, Lu, et al.
Publicado: (2022)

Comparative proteomic analysis of extracellular vesicles isolated from porcine adipose tissue-derived mesenchymal stem/stromal cells
por: Eirin, Alfonso, et al.
Publicado: (2016)

Comparative Proteomic Analysis of Milk-Derived Extracellular Vesicles from Dairy Cows with Clinical and Subclinical Mastitis
por: Wang, Mengling, et al.
Publicado: (2023)

Low-Grade Endometrial Stromal Sarcoma and Uterine Adenosarcoma: A Comparison of Clinical Manifestations and Outcomes
por: Zhang, Yanyan, et al.
Publicado: (2019)

Comparison of the Clinical Outcomes Between Nebulized and Systemic Corticosteroids in the Treatment of Acute Exacerbation of COPD in China (CONTAIN Study): A Post Hoc Analysis
por: Chen, Yahong, et al.
Publicado: (2020)

High-grade endometrial stromal sarcoma: a retrospective study of factors influencing prognosis
por: Zhang, Yan-Yan, et al.
Publicado: (2019)

Nebulized formoterol: a review of clinical efficacy and safety in COPD
por: Gross, Nicholas J, et al.
Publicado: (2010)

Production and Clinical Application of the First Iranian Ultrasonic Desktop Nebulizer
por: Siavash, Mansour, et al.
Publicado: (2018)

Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
por: Bobyleva, Polina I., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6tnen9rf9nr3253478c9ner0kd