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MYC amplifications are common events in childhood osteosarcoma

Osteosarcoma, the most common primary malignant tumour of bone, affects both children and adults. No fundamental biological differences between paediatric and adult osteosarcoma are known. Here, we apply multi‐region whole‐genome sequencing to an index case of a 4‐year‐old child whose aggressive tum...

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Detalles Bibliográficos
Autores principales: De Noon, Solange, Ijaz, Jannat, Coorens, Tim HH, Amary, Fernanda, Ye, Hongtao, Strobl, Anna, Lyskjær, Iben, Flanagan, Adrienne M, Behjati, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363928/
https://www.ncbi.nlm.nih.gov/pubmed/33969640
http://dx.doi.org/10.1002/cjp2.219

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